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Nephrology & Renal Medicine

Acute Phosphate Nephropathy

ICD-10 Code
N14.1_3

AKI caused by the precipitation of calcium-phosphate crystals in the renal tubules. Classically occurs following the administration of oral sodium phosphate bowel purgatives for colonoscopy preparation in high-risk patients.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with acute kidney injury (AKI) following recent colonoscopy preparation using oral sodium phosphate solution. Reports symptoms of nausea, vomiting, lethargy, and decreased urine output starting [X] days post-procedure. No history of pre-existing chronic kidney disease or recent nephrotoxic medication use.

Clinical Examination Findings

Patient appears [distressed/lethargic]. Vitals: BP [X/X] mmHg, HR [X] bpm, Temp [X] C. Physical exam reveals signs of volume depletion including dry mucous membranes, decreased skin turgor, and orthostatic hypotension. No peripheral edema noted.

Treatment Protocol

Immediate cessation of phosphate-containing agents. Aggressive fluid resuscitation with isotonic saline to restore intravascular volume. Monitor serum electrolytes (Ca, PO4, K) and creatinine levels every 6-12 hours. Consider renal replacement therapy (RRT) if severe metabolic derangements or refractory oliguria persist.

Detailed clinical guide coming soon.