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Pediatrics & Neonatology

Ewing Sarcoma, Fibula

ICD-10 Code
C40.22_2

Aggressive malignant bone tumor affecting the fibula, common in pediatric and adolescent patients.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with a persistent, localized pain in the lateral aspect of the lower leg, progressively worsening over [Duration]. Associated with palpable mass, localized swelling, and nocturnal pain. No history of trauma. Systemic symptoms include intermittent low-grade fever, fatigue, and weight loss.

Clinical Examination Findings

Physical examination reveals a firm, non-mobile, tender mass over the fibular shaft. Overlying skin shows erythema and increased local warmth. Neurovascular status of the distal extremity is intact (DP/PT pulses 2+, capillary refill <2s). No palpable inguinal lymphadenopathy. Gait assessment demonstrates an antalgic limp.

Treatment Protocol

Multidisciplinary management initiated. Plan includes neoadjuvant chemotherapy (VIDE/VDC-IE protocol) to achieve tumor shrinkage, followed by surgical resection of the fibula with wide margins. Post-operative adjuvant chemotherapy and consideration for radiotherapy depending on pathological margins and histological response.

Detailed clinical guide coming soon.