Clinical Presentation & Protocol
Patient Usually Complains Of
Patient presents with a persistent, localized dull ache in the right distal thigh, progressively worsening over [Number] weeks. Associated with nocturnal pain, localized swelling, and intermittent low-grade fevers. No history of recent trauma. Systemic symptoms include fatigue and unintentional weight loss.
Clinical Examination Findings
Right lower extremity examination reveals a palpable, firm, non-mobile mass over the distal femoral diaphysis. Localized tenderness to palpation, overlying skin shows increased warmth and prominent superficial venous pattern. Range of motion of the right knee is restricted due to pain. Neurovascular status of the distal limb remains intact.
Treatment Protocol
Multimodal therapeutic approach initiated: Neoadjuvant chemotherapy per [Protocol Name] to achieve tumor cytoreduction, followed by surgical resection of the right femoral lesion with limb-salvage reconstruction. Post-operative adjuvant chemotherapy and radiotherapy to be determined based on histological response and surgical margins.