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Gastroenterology & Hepatology

Fibrolamellar HCC

ICD-10 Code
C22.2

Fibrolamellar HCC - Clinical guidelines.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents for evaluation of a suspected or confirmed fibrolamellar hepatocellular carcinoma (FL-HCC). Clinical history is notable for [absence/presence] of underlying cirrhosis or chronic hepatitis. Presenting symptoms include [abdominal pain/fullness, weight loss, fatigue, or incidental finding]. Review of systems is negative for jaundice or stigmata of chronic liver disease.

Clinical Examination Findings

General: Patient appears [well-nourished/cachectic]. Abdomen: Soft, non-tender, [palpable mass in RUQ/no hepatomegaly]. Skin: No jaundice, spider angiomata, or palmar erythema. Neurologic: Alert and oriented, no asterixis. Cardiovascular/Pulmonary: Regular rate and rhythm, lungs clear to auscultation.

Treatment Protocol

Recommended management includes multidisciplinary tumor board review. Primary treatment modality is complete surgical resection (R0) with regional lymphadenectomy. If unresectable, consider systemic therapy, clinical trials, or locoregional interventions. Post-operative surveillance protocol initiated for monitoring of recurrence.

Detailed clinical guide coming soon.