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Pulmonology / Respiratory

Guillain-Barré Syndrome Respiratory Failure

ICD-10 Code
G61.0

Clinical Criteria for Guillain-Barré Syndrome Respiratory Failure.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with progressive ascending muscle weakness, paresthesias, and recent onset of dyspnea. Symptoms began [Number] days ago following a [GI/Respiratory] infection. Currently exhibiting signs of respiratory muscle fatigue, including orthopnea, shallow breathing, and inability to maintain secretions.

Clinical Examination Findings

Vitals: [HR, BP, SpO2, RR]. Neurological: Symmetric ascending flaccid paralysis, diminished/absent deep tendon reflexes (areflexia). Respiratory: Use of accessory muscles, paradoxical abdominal movement, weak cough reflex, and reduced vital capacity (FVC < 15-20 mL/kg). Bulbar involvement noted by dysphagia and dysarthria.

Treatment Protocol

Immediate admission to ICU for close monitoring of respiratory mechanics (NIF/FVC). Initiate mechanical ventilation if respiratory failure is imminent. Administer IVIG (0.4 g/kg/day for 5 days) or plasma exchange (PLEX). Provide DVT prophylaxis and aggressive pulmonary hygiene.

Detailed clinical guide coming soon.