Clinical Presentation & Protocol
Patient Usually Complains Of
Patient presents with multifocal, infiltrative hepatocellular carcinoma (HCC). Symptoms include progressive abdominal distension, right upper quadrant pain, unintentional weight loss, and fatigue. History significant for [Cirrhosis/Hepatitis B/C/NASH]. No evidence of acute decompensation or hepatic encephalopathy at this time.
Clinical Examination Findings
General: Cachectic appearance, scleral icterus present. Abdomen: Distended, palpable hepatomegaly with irregular, firm liver edge. Positive shifting dullness suggesting ascites. No peripheral edema noted. Cardiovascular/Respiratory: Stable, clear to auscultation.
Treatment Protocol
Plan: Multidisciplinary tumor board review for staging. Given infiltrative nature, consider systemic therapy (e.g., Atezolizumab/Bevacizumab or Tyrosine Kinase Inhibitors) as primary modality. Assess Child-Pugh score and ECOG performance status. Monitor AFP levels and serial cross-sectional imaging.