Clinical Presentation & Protocol
Patient Usually Complains Of
Patient presents with a progressive history of involuntary choreiform movements, cognitive decline, and psychiatric disturbances. Onset of symptoms is insidious, characterized by motor impersistence, gait instability, and executive dysfunction. Family history is positive for autosomal dominant inheritance pattern.
Clinical Examination Findings
General physical examination reveals cachexia or significant weight loss despite adequate caloric intake. Vital signs are stable, though autonomic instability may be noted. Skin integrity is intact; no signs of secondary trauma despite frequent falls.
Treatment Protocol
Management plan includes symptomatic treatment for chorea with VMAT2 inhibitors (e.g., tetrabenazine or deutetrabenazine) or antipsychotics (e.g., risperidone). Multidisciplinary approach initiated: physical therapy for gait/balance, speech therapy for dysarthria/dysphagia, and psychiatric support for mood stabilization.