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Pediatrics & Neonatology

Kawasaki Disease

ICD-10 Code
M30.3

Clinical Criteria for Kawasaki Disease.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with persistent high-grade fever for [Number] days, unresponsive to antipyretics. Associated symptoms include bilateral non-exudative conjunctivitis, oropharyngeal changes (erythematous pharynx, strawberry tongue, cracked lips), polymorphous rash, extremity changes (erythema/edema of hands/feet), and cervical lymphadenopathy (>1.5 cm). No alternative diagnosis identified.

Clinical Examination Findings

Vitals: T [Temp], HR [Rate], BP [Pressure]. General: Irritable, febrile. HEENT: Bilateral bulbar conjunctival injection without exudate; erythematous oropharynx, fissured lips, strawberry tongue. Neck: Unilateral cervical lymphadenopathy [Size] cm. Skin: Polymorphous rash (maculopapular/scarlatiniform) on trunk/perineum. Extremities: Indurated edema of hands and feet; periungual desquamation noted. Cardiac: S1/S2 regular, no murmurs.

Treatment Protocol

Initiate IVIG 2g/kg as a single infusion over 10-12 hours. Administer high-dose Aspirin (80-100 mg/kg/day divided q6h) until afebrile for 48 hours, then transition to low-dose Aspirin (3-5 mg/kg/day) for 6-8 weeks. Monitor echocardiogram at diagnosis, 2 weeks, and 6-8 weeks for coronary artery aneurysms.

Detailed clinical guide coming soon.