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Pediatrics & Neonatology

Leukemia (Acute Lymphoblastic - ALL)

ICD-10 Code
C91.00

Clinical Criteria for Leukemia (Acute Lymphoblastic - ALL).

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with a history of [duration] characterized by persistent fatigue, unexplained fevers, and recurrent infections. Caregivers report noticeable pallor, easy bruising, and petechiae. Associated symptoms include bone/joint pain, night sweats, and unintentional weight loss. No history of recent trauma or known bleeding diathesis.

Clinical Examination Findings

General: Patient appears pale and ill-appearing. HEENT: Conjunctival pallor noted; no scleral icterus. Lymphatic: Generalized lymphadenopathy present (cervical, axillary, inguinal). Cardiovascular: Tachycardic, regular rhythm, grade [1-6]/6 systolic murmur. Respiratory: Clear to auscultation bilaterally. Abdomen: Hepatomegaly and splenomegaly noted on palpation; no rebound tenderness. Skin: Multiple ecchymoses and petechiae noted on extremities and trunk.

Treatment Protocol

Initiate induction chemotherapy protocol per [Protocol Name/COG]. Supportive care: Transfusion of irradiated, leukoreduced PRBCs and platelets as indicated. Prophylactic antibiotics/antifungals initiated. Hydration with IV fluids and allopurinol for tumor lysis syndrome prophylaxis. Central venous access established.

Detailed clinical guide coming soon.