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Gastroenterology & Hepatology

Listeria monocytogenes (Food-borne - Immunocompromised)

ICD-10 Code
A32.9

Listeria monocytogenes (Food-borne - Immunocompromised) - Clinical guidelines.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient is an immunocompromised individual presenting with acute onset of fever, myalgia, and gastrointestinal distress following the consumption of high-risk food items (e.g., deli meats, unpasteurized dairy). Symptoms include nausea, vomiting, and watery diarrhea. Patient reports recent onset of headache or neck stiffness, raising concern for systemic dissemination.

Clinical Examination Findings

General: Febrile, appears ill, signs of dehydration. HEENT: Nuchal rigidity present/absent, photophobia. Cardiovascular: Tachycardic, regular rhythm. Abdominal: Soft, non-distended, hyperactive bowel sounds, diffuse mild tenderness without rebound or guarding. Neurological: Alert and oriented, focal neurological deficits absent/present. Skin: No rashes noted.

Treatment Protocol

Initiate empiric intravenous antibiotic therapy with Ampicillin (2g IV q4h) plus Gentamicin (synergistic dosing) for 14-21 days. Adjust dosage based on renal function. Monitor CBC, electrolytes, and inflammatory markers. If CNS involvement is suspected, perform lumbar puncture and consider adding Ceftriaxone if alternative pathogens are suspected.

Detailed clinical guide coming soon.