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Gastroenterology & Hepatology

Ménétrier's Disease (Giant Hypertrophic Gastritis)

ICD-10 Code
K31.8_2

Ménétrier's Disease (Giant Hypertrophic Gastritis) - Clinical guidelines.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with a history of epigastric pain, early satiety, and postprandial bloating. Associated symptoms include significant weight loss, nausea, and occasional vomiting. History of protein-losing enteropathy symptoms, including peripheral edema or hypoalbuminemia, noted. No history of NSAID abuse or H. pylori infection.

Clinical Examination Findings

Physical examination reveals epigastric tenderness on deep palpation. Assessment for signs of protein-losing enteropathy, including pitting edema in lower extremities. Evaluation of nutritional status indicates cachexia or muscle wasting. Abdominal auscultation is unremarkable.

Treatment Protocol

Management plan includes high-protein, low-fat diet. Pharmacotherapy initiated with PPIs (e.g., Omeprazole) or H2-receptor antagonists to reduce gastric acid secretion. Consider Cetuximab (anti-EGFR monoclonal antibody) for refractory cases. Monitor serum albumin levels and nutritional status. Surgical consultation for partial or total gastrectomy in cases of severe hemorrhage or suspected malignancy.

Detailed clinical guide coming soon.