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Pediatrics & Neonatology

Non-Ossifying Fibroma (NOF), Distal Femur

ICD-10 Code
D16.21_3

Extremely common benign fibrous lesion of childhood that usually resolves spontaneously. Also known as Fibrous Cortical Defect.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents for evaluation of a distal femoral lesion incidentally discovered on imaging. Patient denies localized pain, swelling, or mechanical symptoms. No history of trauma, night pain, or systemic constitutional symptoms. Lesion characteristics consistent with non-ossifying fibroma (NOF).

Clinical Examination Findings

Musculoskeletal exam of the distal femur reveals no palpable mass, erythema, or warmth. Range of motion of the knee is full and painless. No joint effusion or ligamentous laxity noted. Neurovascular status of the distal extremity is intact.

Treatment Protocol

Observation is the standard of care for asymptomatic NOF. Serial radiographic follow-up is recommended to monitor for spontaneous regression or ossification. Activity modification is not required unless the lesion is large and poses a risk of pathologic fracture.

Detailed clinical guide coming soon.