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Pulmonology / Respiratory

Non-Specific Interstitial Pneumonia (NSIP) - Cellular

ICD-10 Code
J84.113

Clinical Criteria for Non-Specific Interstitial Pneumonia (NSIP) - Cellular.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with a subacute to chronic history of progressive exertional dyspnea and persistent non-productive cough. Denies constitutional symptoms such as significant weight loss or fever. No history of occupational dust exposure, hypersensitivity pneumonitis triggers, or connective tissue disease symptoms (e.g., Raynaud’s, arthralgias, or sicca symptoms). Symptoms have been present for [Duration], with gradual worsening of exercise tolerance.

Clinical Examination Findings

Respiratory examination reveals bilateral fine end-inspiratory crackles (Velcro-like) at the lung bases. No evidence of digital clubbing. Cardiovascular exam is unremarkable; no signs of right heart failure or elevated JVP. Oxygen saturation is [Value]% on room air at rest, with [Value]% desaturation noted upon exertion.

Treatment Protocol

Initiate immunosuppressive therapy with systemic corticosteroids (e.g., Prednisone [Dose] mg daily) with a planned tapering schedule. Consider steroid-sparing agents such as Mycophenolate Mofetil or Azathioprine if response is suboptimal or to facilitate steroid withdrawal. Monitor pulmonary function tests (PFTs) and DLCO every 3-6 months. Smoking cessation and avoidance of pulmonary irritants are strictly advised.

Detailed clinical guide coming soon.