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Orthopedics & Traumatology

Osteosarcoma, Proximal Fibula

ICD-10 Code
C40.22_3

Primary malignant bone tumor arising in the proximal end of the fibula near the knee.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with progressive, deep-seated pain in the proximal lateral aspect of the lower extremity, exacerbated by activity and nocturnal rest. Notable for localized swelling, palpable firm mass near the fibular head, and progressive functional impairment of the knee joint. No history of recent trauma. Systemic symptoms include unexplained weight loss and fatigue.

Clinical Examination Findings

Physical examination reveals a firm, non-mobile, tender mass localized to the proximal fibula. Overlying skin shows prominent superficial venous engorgement. Knee range of motion is restricted by pain and mass effect. Neurovascular assessment of the common peroneal nerve is critical; check for foot drop or sensory deficits in the first dorsal web space. Distal pulses are intact.

Treatment Protocol

Multidisciplinary management initiated. Plan includes neoadjuvant chemotherapy to achieve tumor necrosis, followed by surgical resection (en bloc resection of the proximal fibula). Reconstruction options include allograft or autograft stabilization. Post-operative physical therapy and long-term surveillance for local recurrence and pulmonary metastasis are mandatory.

Detailed clinical guide coming soon.