Clinical Presentation & Protocol
Patient Usually Complains Of
Patient presents for follow-up of high-grade pancreatic intraepithelial neoplasia (PanIN-3) identified on recent histopathology. Patient denies abdominal pain, jaundice, steatorrhea, or unintentional weight loss. Current clinical status is asymptomatic with no evidence of obstructive symptoms or systemic malignancy.
Clinical Examination Findings
Abdominal examination: Soft, non-tender, non-distended. No palpable masses or organomegaly. Bowel sounds normoactive. No evidence of jaundice or scleral icterus. ECOG performance status: 0.
Treatment Protocol
Plan: Surgical consultation for consideration of pancreatic resection (e.g., Whipple procedure or distal pancreatectomy) given the high-grade nature of PanIN-3. Surveillance imaging (MRI/MRCP or EUS) scheduled. Discussion regarding potential for progression to invasive ductal adenocarcinoma.