Clinical Presentation & Protocol
Patient Usually Complains Of
Patient presents for follow-up of histopathologically confirmed High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) identified on recent prostate needle biopsy. Patient is currently asymptomatic regarding obstructive or irritative voiding symptoms. No history of gross hematuria or pelvic pain. PSA levels are monitored for trends.
Clinical Examination Findings
Digital Rectal Examination (DRE) reveals a prostate of [Size: e.g., 30cc] with [Consistency: e.g., smooth, firm, non-tender]. No palpable nodules, induration, or asymmetry suggestive of invasive carcinoma detected. No evidence of pelvic lymphadenopathy.
Treatment Protocol
Management plan involves active surveillance with serial PSA monitoring every 3-6 months. Repeat prostate biopsy is indicated if PSA velocity increases or if DRE findings change. Consider chemoprevention or lifestyle modifications to reduce prostate cancer risk.