Menu
Nephrology & Renal Medicine

Retroperitoneal Fibrosis (Ormond's Disease)

ICD-10 Code
N13.5

Rare disorder characterized by the development of extensive fibrous tissue in the retroperitoneum. Often entraps and compresses the ureters, causing bilateral hydronephrosis and progressive renal failure. Can be idiopathic, IgG4-related, or drug-induced.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with a history of [chronic/subacute] flank or lower back pain, accompanied by [weight loss/fatigue/fever]. Review of systems is significant for [urinary frequency/hesitancy/anuria]. History notable for [known autoimmune disease/IgG4-related disease/recent medication use]. Symptoms are progressive, raising concern for ureteral obstruction and renal impairment.

Clinical Examination Findings

General: Patient appears [well-developed/ill-appearing/distressed]. Vitals: [BP/HR/Temp]. Abdomen: Soft, non-tender, though deep palpation may reveal a vague, non-pulsatile midline mass. Extremities: [Presence/absence] of lower extremity edema. Skin: No evidence of rashes or vasculitic lesions.

Treatment Protocol

Plan: 1. Initiate corticosteroid therapy (e.g., Prednisone [dose] mg/day) to induce remission. 2. Urological consultation for ureteral stenting or nephrostomy if obstructive uropathy is present. 3. Consider immunosuppressive agents (e.g., Mycophenolate Mofetil/Tamoxifen) for refractory cases. 4. Monitor renal function (Cr/GFR) and inflammatory markers (ESR/CRP) serially.

Detailed clinical guide coming soon.