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respiratory

Chronic Pulmonary Aspergillosis (CPA)

ICD-10 Code
B44.1

Clinical Criteria for Chronic Pulmonary Aspergillosis (CPA).

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with a chronic respiratory history (>3 months) characterized by productive cough, intermittent hemoptysis, progressive dyspnea, and constitutional symptoms including unintentional weight loss, fatigue, and night sweats. History significant for underlying lung disease (e.g., prior TB, COPD, or sarcoidosis). No acute distress noted; symptoms are persistent and refractory to standard antibiotic therapy.

Clinical Examination Findings

General: Patient appears chronically ill, cachectic. Respiratory: Auscultation reveals localized crackles or bronchial breath sounds, most commonly in the upper lobes. Percussion may show dullness. Signs of clubbing may be present. Cardiovascular: Regular rate and rhythm, no murmurs. Extremities: No peripheral edema.

Treatment Protocol

Initiate long-term antifungal therapy (e.g., Itraconazole or Voriconazole). Monitor liver function tests and therapeutic drug levels. Consider surgical resection for localized aspergilloma with severe hemoptysis. Bronchial artery embolization indicated for acute, life-threatening hemoptysis. Pulmonary rehabilitation and optimization of underlying lung disease management.

Detailed clinical guide coming soon.