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Gastroenterology & Hepatology

Encephalitozoon intestinalis (Disseminated infection)

ICD-10 Code
A07.8_6

Encephalitozoon intestinalis (Disseminated infection) - Clinical guidelines.

Clinical Presentation & Protocol

Patient Usually Complains Of

Patient presents with chronic, non-bloody, watery diarrhea, abdominal cramping, and significant weight loss. History significant for severe immunocompromise (e.g., advanced HIV/AIDS with low CD4 count). Symptoms are progressive, associated with malabsorption, and unresponsive to standard anti-diarrheal therapy. Potential systemic involvement noted, including ocular irritation or respiratory symptoms.

Clinical Examination Findings

General: Patient appears cachectic and chronically ill. HEENT: Possible conjunctival injection or keratoconjunctivitis. Abdomen: Soft, non-distended, hyperactive bowel sounds, mild diffuse tenderness on palpation, no rebound or guarding. Skin: Signs of dehydration, poor skin turgor. Neurological: Alert and oriented, no focal deficits.

Treatment Protocol

Initiate Albendazole 400 mg orally twice daily. Duration of therapy is prolonged, typically 2-4 weeks or longer depending on immune reconstitution. Monitor liver function tests (LFTs) and complete blood count (CBC) periodically. Address underlying immunosuppression (e.g., optimize ART in HIV patients). Supportive care: Oral rehydration therapy, electrolyte replacement, and nutritional support.

Detailed clinical guide coming soon.